Human Bone strength Evaluation through different Mechanical Tests

Human Bone strength Evaluation through different Mechanical Tests

Bone mineral density [BMD] generally correlates with bone strength. BMD testing is used to assess bone density and diagnose osteoporosis. The correlation between CT numbers and mechanical property estimated from cortical bone were found to be low (r2<0.2) and cancellous bone were found to be higher (r2>0.6). The specific relationship depending on the types of bone, that predict elastic module f...

[Direct measurement of bone mechanical strength].

Bone Generation through Mechanical Loading

Bones are dynamic and responsive organs, they regulate their strength and mass according to the loads which they are subjected. Because, the Wnt/β-catenin pathway has profound effects on the regulation of bone mass, we hypothesized that mechanical loading of bone cells stimulates Wnt/β-catenin signaling, which results in the generation of new bone mass. Mechanical loading triggers the secretion...

Changes in bone mechanical strength in response to physical therapy.

Numerous unfavorable factors that disturb the balance between resorption and bone formation affect bone mechanical strength. Also mechanical loading (body mass and muscle tension) and risk factors for osteoporosis affect bone strength. Loading that can be applied to the bone is limited by bone structure. At the same time, loading applied to the bone may condition its structure. This is possible...

Measurement of the differences in trabecular bone mechanical strength

The X-ray microtomography (XMT) pioneered by Elliot and Dover in 1982 [1] was developed and used in many studies [2] until now. While XMT is becoming a common technique in the laboratory studies, a standard for quantitative determination of the absolute material density distribution has not been attained. To date, a quantitative method of bone measurement on the microstructural level is not com...